課程資訊
課程名稱
博士專題研究
Seminar 
開課學期
100-2 
授課對象
醫學工程學研究所  
授課教師
謝銘鈞 
課號
Biomed8001 
課程識別碼
548 D0020 
班次
10 
學分
全/半年
半年 
必/選修
選修 
上課時間
 
上課地點
 
備註
本課程中文授課,使用英文教科書。
總人數上限:30人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1002Biomed8001_10 
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課程概述

博士專題研究 

課程目標
無 
課程要求
1.每星期挑選一主題報告與同學進行討論。
2.同學分享每星期實驗進度,並由老師給予改善建議。 
預期每週課後學習時數
 
Office Hours
每週二 17:30~20:00 
指定閱讀
無 
參考書目
無 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
出席 
50% 
 
2. 
報告 
50% 
 
 
課程進度
週次
日期
單元主題
第2週
02/28  二二八國定假日放假 
第3週
03/13  1.Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity 2.The mucoadhesive and gastroretentive properties of hydrophobin-coated porous silicon nanoparticle oral drug delivery systems 
第4週
03/20  1.Antibody-Targeted Nanovectors for the Treatment of Brain Cancers 2.Control by pulse parameters of DNA electrotransfer into solid tumors in mice 
第5週
03/27  1.Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab 2.Nicotine increases cancer stem cell population in MCF-7 cells 3.The enhancement of cancer stem cell properties of MCF-7 cells in 3D collagen scaffolds for modeling of cancer and anti-cancer drugs 
第6週
04/03  1.EGFR Kinase Promotes Acquisition of Stem Cell-Like Properties: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma Stem Cells 2.Protease inhibition and absorption enhancement by functional nanoparticles for effective oral insulin delivery 
第7週
04/10  1.Internalization of C60 fullerenes into cancer cells with accumulation
in the nucleus via the nuclear pore complex 2.siRNA nanocarriers based on methacrylic acid copolymers 
第8週
04/17  期中考 
第9週
04/24  1.Thermo-responsive shell cross-linked PMMA-b-P(NIPAAm-co-NAS) micelles for drug delivery 2.Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33 
第10週
05/01  1.The accumulation of dual pH and temperature responsive micelles in tumors 2.“OA02” Peptide Facilitates the Precise Targeting of Paclitaxel-Loaded Micellar Nanoparticles to Ovarian Cancer In Vivo 
第11週
05/08  1.Cisplatin@US-tube carbon nanocapsules for enhanced chemotherapeutic delivery 2.Pharmaceutical Compositions For Treating Tumors And Use Thereof 
第12週
05/15  1.3D in vitro bioengineered tumors based on collagen I hydrogels 2.Chitosan-based scaffolds for the support of smooth muscle constructs in intestinal tissue engineering 
第13週
05/22  1.Exchange-coupled magnetic nanoparticles for efficient heat induction 2.Opening of Epithelial Tight Junctions and Enhancement of Paracellular Permeation by Chitosan: Microscopic, Ultrastructural, and Computed-Tomographic Observations 
第14週
05/29  1.SNAIL Regulates Interleukin-8 Expression, Stem Cell–Like Activity, and Tumorigenicity of Human Colorectal Carcinoma Cells 2.
The use of an in vitro 3D melanoma model to predict in vivo plasmid transfection using electroporation 
第15週
06/05  1.In vivo tumor imaging using a novel RNAi-based detection mechanism 2.Normal and neoplastic nonstem cells can
spontaneously convert to a stem-like state 
第16週
06/12  1.Cell-penetrating peptide mimicking polymer-based combined delivery of paclitaxel and siRNA for enhanced tumor growth suppression 2.Expression of Mesenchymal Markers Vimentin and Fibronectin: The Clinical Significance in Esophageal Squamous Cell Carcinoma 
第17週
06/19  期末考